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Molecular Pathobiology PhD/MPhil – (Ph.D.)

University of Birmingham

School of Education
Application Deadline: None, but early application advised
Annual Tuition Fee: ≈ € 4,232 - ≈ € 29,400 (non-EEA)
Location: Birmingham / United Kingdom / View location on map ▾ Hide location on map ▴
Duration: 48 months Start Date: September
Education Variants:
  • Fulltime
Project type:
  • Open PhD programme
Languages: English 
-1.929801,52.449985

Location of University of Birmingham

Molecular Pathobiology analyses molecular mechanisms of human disease and toxicity focusing on signalling, metabolism and gene expression in dysregulated differentiation, proliferation and survival in vitro and in vivo. Molecular Pathobiology members champion genetic, transcriptomic, metabolomic, bioinformatic and systems approaches to the prevention and treatment of human disease and sustaining and improving environmental health.

Research areas

The research activities of the Molecular Pathobiology theme within the School seek to understand the molecular bases of disease and toxic processes (pathobiology). Our studies focus on alteration of cell signalling, metabolites and gene expression, particularly in the dysregulation of cell differentiation, proliferation and survival in vitro and in vivo. Particular interests are:

* The understanding of disease
* Improvement of human health through the prevention and treatment of disease
* Sustaining and improving the wellbeing of the environment
* Development and use of ‘omic’ technologies and associated bioinformatics

Key facts

Type of Course: Doctoral research

Duration: PhD – 3 and 4 years full-time; MPhil – 1 year full-time

Start date: September 2011


Contents

Research interests of staff

* Development of novel strategies for treatment of haematological and lymphoid malignancies. Contact: Dr Chris Bunce
Tel: +44 (0)121 414 3770
Email: c.m.bunce@bham.ac.uk
* Cell toxicology, molecular mechanisms and ecotoxicology. Contact: Professor Kevin Chipman
Tel: +44 (0)121 414 5422/5420
Email: j.k.chipman@bham.ac.uk
* Analysis of large-scale gene expression microarrays. Contact: Dr Francesco Falciani
Tel: +44 (0)121 414 5400
Email: f.falciani@bham.ac.uk
* Genetic toxicity; oxidative stress; DNA repair. Contact: Dr Nick Hodges
Tel: +44 (0)121 414 3386
Email: n.hodges@bham.ac.uk
* The evolution of virulence in the human fungal pathogen Cryptococcus neoformans. Contact: Dr Robin May
Tel: +44 (0)121 414 5418
Email: r.c.may@bham.ac.uk
* Calcium: signalling, homeostasis, ATPase; IP3 and ryanodine receptors. Contact: Dr Frank Michelangeli
Tel: +44 (0)121 414 5398/5394
Email: f.michelangeli@bham.ac.uk
* Pterin metabolism and neurological disease. Contact: Dr Anne Pheasant
Tel: +44 (0)121 414 5409
Email: a.e.pheasant@bham.ac.uk
* Probabilistic prediction of bacterial operons using genome sequence and gene expression data. Contact: Dr Dov Stekel
Tel: +44 (0)121 414 4209
Email: d.j.stekel@bham.ac.uk
* Liver metabolism. Contact: Professor Alastair Strain
Tel: +44 (0)121 414 3669
Email: a.j.strain@bham.ac.uk
* Metabolomic approaches for characterising molecular responses to environmental stress. Contact: Dr Mark Viant
Tel: +44 (0)121 414 2219
Email: m.viant@bham.ac.uk
* Human toxicology Contact: Dr Rosemary Waring
Tel: +44 (0)121 414 5421/5420
Email: r.h.waring@bham.ac.uk

IELTS

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Requirements

At least a 2.1 Honours degree or equivalent in a relevant subject

Ensure your qualifications meet our entry requirements for research degrees

To gain admission to a research degree programme (with the exception of the Doctor of Dental Surgery (DDS) or Doctor of Medicine (MD)) an applicant must comply with the following entry requirements:

* Attainment of an Honours degree (normally a First or Upper Second Class Honours degree or equivalent) in a relevant subject awarded by an approved university, or
* Attainment of an alternative qualification or qualifications and/or evidence of experience judged by the University as indicative of an applicant’s potential for research and as satisfactory for the purpose of entry to a research degree programme.

In addition:

* Admission and registration for a research degree programme may be conditional on satisfactory completion of preliminary study, which may include assessment.
* In some cases you will also need to have completed a Masters degree or equivalent qualification in a relevant subject.

Please note

* Entry onto many programmes is highly competitive, therefore we consider the skills, attributes, motivation and potential for success of an individual when deciding whether to make an offer.
* Specific entry requirements are given for each programme. Any academic and professional qualifications or industrial experience you may have are normally taken into account, and in some cases form an integral part of the entrance requirements. If your qualifications are non-standard or different from the entry requirements stated in the online prospectus, please contact the relevant school or department to discuss whether your application would be considered.
* After we have received your application you may, if you live in the UK, be invited for an interview or to visit us to discuss your application.

Additional Requirements

Minimal degree required: Master's degree
Minimal amount of work experience Not specified

Language Proficiency

IELTS Band: 6.5
TOEFL Internet-based: 93

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