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Cellular Pathology and Molecular Genetics – (Ph.D.)
Anglia Ruskin University, Cambridge Campus
Faculty of Science & Technology| Application Deadline: | January 15 | ||
| Annual Tuition Fee: | ≈ € 5,200 - ≈ € 12,070 (non-EEA) | ||
| Location: | Cambridge / United Kingdom / View location on map ▾ Hide location on map ▴ | ||
| Duration: | 36 months | Start Date: | January, September |
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| Languages: | English | ||
Location of Anglia Ruskin University, Cambridge Campus
Our research interests involve molecular mechanisms that underpin the pathogenesis and aetiology of mammalian diseases, such as rheumatoid arthritis and cardiovascular disease and chronic myeloproliferative diseases.
Current projects include:
* investigation of cryptic genomic biomarkers in human patients with myeloproliferative disease
* investigation into the mechanism by which human recombinant erythropoietin (rHuEPO) modulates glycoaminoglycan turnover in a nitric oxide synthase (NOS)-dependent porcine explant model of rheumatoid arthritis
* the molecular genetics of the melanocortin receptor (MC1R)
* the role of transglutaminase enzymes in cell cycle control and cell death
* cellular biology of natural products including drugs and antioxidants
* mechanisms underpinning glycation chemistry in models of oxidative disease states.
Contents
The Cellular Pathology and Molecular Genetics Group occupies two fully dedicated, tissue culture laboratories and one molecular biology research laboratory on-site in our Cambridge campus. Specialist features include our own dedicated flow cytometer and access to gene sequencing facilities on site. Post graduate research is supported by two full time research assistants.
Training courses in a variety of key biological techniques, such as polymerase chain reaction (PCR) and cell biology are available on site, together with an established formal programme-long training portfolio in scientific wring and related skills.
Facilities
Our facilities include:
* tissue culture (developing cell transfection expression systems)
* different cell lines (Swiss 3T3 fibroblasts, HepG2 hepatocytes and CAKI-2 kidney cells)
* flow cytometry
* FISH - Fluorescence in situ hybridization
* PCR genetics (real time PCR and standard PCR)
* biochemistry (i.e. SDS page / Western blotting)
* DNA sequencing facilities.
IELTS
You are normally required to take an English Proficiency Test.
Most European Universities recognise the IELTS test.
Take testRequirements
Candidates seeking admission to the degree of MPhil or MPhil with possibility of transfer to PhD will normally be required to hold a first or upper second class honours degree of a university, or any other institution of higher education in the UK with degree-awarding powers or a qualification which is regarded by Anglia Ruskin as equivalent to a first or upper second class honours degree.
Additional Requirements
| Minimal degree required: | Master's degree |
| Minimal amount of work experience | Not specified |
Language Proficiency
| IELTS Band: | 6.5 |
| TOEFL Paper-based: | 600 |
| TOEFL Computer-based: | 250 |
| TOEFL Internet-based: | 100 |
Faculty
Staff Research
- Dr Peter Coussons (Head of Cellular Pathology and Molecular Genetics Group) BSc, PhD (Senior lecturer Biomedical Science) - role of Transglutaminase enzymes in health and disease; Oxidative aspects of chronic disease
- Dr Alison Thomas, BSc, PhD (Senior lecturer Genetics) - genetic analysis of environmental effects in animal populations
- Dr Leigh Stoeber BSc, PhD (Senior lecturer Biomedical Science) - molecular markers of cell cycle control
- Dr Beverley Vaughan BSc, PhD (Senior lecturer Biomedical Science) - cellular toxicity of piperazine based pharmaceuticals
- Dr David Hughes, BSc, PhD (Senior lecturer Biomedical Science) - nutritional effectors of cell signalling
- Mrs Helen McRobie, BSc, (Lecturer in Biomedical Science) - role of Melanocortin receptor (MC1R in control of pigmentation)
- Mrs Jocelyn Pryce, BSc, PhD (Lecturer Biomedical Science) - histopathology of disease
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